Name: Delicious Chicken Alfredo Lasagna Roll-Ups for Cozy Nights
Prep time: 20 min
Cook time: 30 min
Total time: 60 min
Ingredients: 12 oz Lasagna Noodles (Use cooked or no-boil noodles.); 2 cups Cooked Chicken (Leftover rotisserie chicken works well.); 15 oz Ricotta Cheese; 1 cup Cooked Spinach (Squeeze out excess water.); 1 large Egg (Can be omitted for a dairy-free version.); 2 cups Mozzarella Cheese (Or substitute with shredded provolone.); 1/4 cup Parmesan Cheese (Pecorino can be used as an alternative.); to taste Salt; to taste Pepper; 2 cups Alfredo Sauce (Store-bought or homemade.)

As I stood in my kitchen, the aroma of garlic and creamy sauce wafted through the air, making my mouth water. I couldn’t help but smile, knowing that soon, I’d be savoring my favorite comfort food: Chicken Alfredo Lasagna Roll-Ups. This dish perfectly marries tender lasagna noodles with a luscious filling of juicy chicken, ricotta cheese, and fresh spinach, all enveloped in a rich Alfredo sauce. With just a bit of prep time, this easy recipe is a delightful way to bring families together around the dinner table. Plus, they’re make-ahead friendly—perfect for busy evenings or unexpected guests! Ready to fall in love with your new favorite dinner? Let’s dive in!

Why is this dish a game-changer?

Simplicity: These Chicken Alfredo Lasagna Roll-Ups are incredibly easy to prepare, perfect for both home cooks and culinary wizards alike.

Flavor Explosion: The rich combination of creamy Alfredo, flavorful chicken, and savory cheeses ensures every bite is a delight.

Make-Ahead Magic: Prepare these roll-ups in advance for a hassle-free dinner option that still feels gourmet, making it a lifesaver for busy nights.

Family Favorite: This dish appeals to all ages, transforming ordinary dinners into fun, interactive meals that will be requested again and again.

Versatile Filling: Feel free to swap out the chicken for a different protein or load them with your favorite veggies—like mushrooms or zucchini—making it adaptable for any preference.

Chicken Alfredo Lasagna Roll-Ups Ingredients

For the Roll-Ups
• Lasagna Noodles – Use cooked or no-boil noodles; if using no-boil, add extra sauce or water for optimal texture.
• Cooked Chicken – This is your main protein source; leftover rotisserie chicken makes for a quick substitute.
• Ricotta Cheese – Provides creaminess and richness in the filling; cottage cheese is a lighter option if desired.
• Cooked Spinach – Adds nutrition and moisture; make sure to squeeze out excess water, or use thawed frozen spinach.
• Egg – Binds the filling together; you can omit this for a dairy-free version and use a suitable binder instead.
For Assembly
• Mozzarella Cheese – Offers a gooey topping; feel free to substitute with shredded provolone for a different flavor.
• Parmesan Cheese – Adds a sharp, salty flavor; pecorino can be used as an alternative for a unique twist.
• Salt and Pepper – Enhance the overall flavors of your dish.
• Alfredo Sauce – A creamy coating for the roll-ups; store-bought is convenient, but homemade offers a fresh taste.

You’re all set to whip up these delightful Chicken Alfredo Lasagna Roll-Ups! Enjoy the comfort of this dish, perfect for family gatherings or a cozy evening at home.

Step‑by‑Step Instructions for Chicken Alfredo Lasagna Roll-Ups

Step 1: Preheat Oven
Begin by preheating your oven to 375°F (190°C). While the oven warms up, grease a 9×13-inch baking dish with non-stick cooking spray or a little olive oil. This will ensure that your Chicken Alfredo Lasagna Roll-Ups won’t stick while baking, allowing for easy serving and cleanup.

Step 2: Prepare Filling
In a large mixing bowl, combine ricotta cheese, cooked spinach, the egg, 1 cup of mozzarella, 1/4 cup of parmesan, and a pinch of salt and pepper. Fold in the shredded chicken gently until everything is well combined. This creamy filling will bring your Chicken Alfredo Lasagna Roll-Ups to life, so be sure to blend the ingredients thoroughly for a luscious texture.

Step 3: Roll Noodles
Lay out each lasagna noodle on a clean surface. Spread a generous layer of the chicken and cheese mixture evenly over each noodle. Starting at one end, roll the noodle tightly around the filling, creating a beautiful roll-up. Place the rolled noodles seam-side down in your prepared baking dish, ensuring they are snug against each other.

Step 4: Assemble Dish
Pour 1 cup of Alfredo sauce evenly across the bottom of your greased baking dish, creating a flavorful base. Carefully arrange the lasagna roll-ups in the dish, making sure they are seam-side down. Drizzle the remaining Alfredo sauce over the top and sprinkle the rest of the mozzarella and parmesan cheese to create a cheesy crust that will melt beautifully.

Step 5: Bake
Cover the baking dish with aluminum foil to prevent excessive browning. Bake your Chicken Alfredo Lasagna Roll-Ups in the preheated oven for 25 minutes, allowing the flavors to meld and the cheese to begin melting. After the time is up, carefully remove the foil and broil on high for an additional 2-3 minutes until the top is golden and bubbly.

Step 6: Cool and Serve
Once baked, take the dish out of the oven and let it cool for about 5-10 minutes. This resting period helps the Chicken Alfredo Lasagna Roll-Ups set and makes them easier to serve. Garnish with freshly chopped parsley or basil for a pop of color before slicing and sharing this delicious comfort food with your family and friends.

What to Serve with Chicken Alfredo Lasagna Roll-Ups

Create a delightful dining experience that elevates your Chicken Alfredo Lasagna Roll-Ups from a simple meal to a memorable feast.

Garlic Bread: Warm, buttery garlic bread is perfect for soaking up the creamy Alfredo sauce, making every bite an indulgent treat.
Simple Green Salad: A crisp salad with fresh greens and a zesty vinaigrette adds a refreshing contrast, balancing the richness of the lasagna roll-ups. The vibrant colors and textures will brighten your table and your palate.
Roasted Vegetables: Seasoned, roasted veggies like zucchini and bell peppers provide a delightful crunch and add a nutritious touch to your meal.
Steamed Broccoli: The mild bitterness of steamed broccoli complements the rich flavors of the Chicken Alfredo, creating a harmonious balance of taste and texture.
Italian Herb Risotto: Creamy risotto with a hint of parmesan and herbs enhances the Italian flavors in this meal and is a comforting side dish option.
Wine Pairing: A crisp white wine, like Pinot Grigio or Chardonnay, complements the creamy Alfredo beautifully while refreshing your palate between bites.

Chicken Alfredo Lasagna Roll-Ups Ideas

Customize your Chicken Alfredo Lasagna Roll-Ups to suit your taste and dietary needs while keeping that comforting essence alive!

Dairy-Free: Replace ricotta and mozzarella with plant-based cheese alternatives for a creamy consistency without dairy.
Vegetarian Delight: Opt for sautéed mushrooms, zucchini, or bell peppers instead of chicken for a delicious, meat-free option. This swap adds a fresh crunch that complements the creamy sauce beautifully.
Spicy Kick: Mix in some crushed red pepper flakes or diced jalapeños to the filling. Adding a little heat elevates the flavor profile without overpowering the dish.
Pasta Variants: Use spinach or whole wheat lasagna noodles for added nutrition. The whole wheat option offers a heartier flavor that pairs wonderfully with Alfredo.
Protein Boost: Swap chicken for shredded beef or ground turkey to mix things up. Each protein brings unique flavors, making the roll-ups versatile for various tastes.
Herb Infusion: Incorporate fresh herbs like basil or parsley into the filling for bursts of flavor. This will brighten each bite and give your rolls an aromatic touch!
Alfredo Upgrade: Try using a homemade Alfredo sauce for a richer taste. Nothing beats the savoriness of freshly made sauce that envelops these roll-ups.
Serve with Style: Pair your roll-ups with a fresh garden salad or a side of garlic bread, similar to serving alongside a plate of Bang Bang Chicken Sliders. It creates a lovely, comforting dinner experience that everyone will enjoy!

Make Ahead Options

These Chicken Alfredo Lasagna Roll-Ups are a fantastic option for meal prep enthusiasts! You can assemble the roll-ups up to 24 hours in advance and refrigerate them, ensuring they stay fresh and delicious. To maintain quality, keep them covered with foil to prevent drying out. When you’re ready to bake, simply take them from the fridge, pour additional Alfredo sauce over the top, and bake for an extra 10-15 minutes, since they’ll be cold. Not only do these make-ahead roll-ups save you time on busy weeknights, but they also allow the flavors to meld beautifully, resulting in a cozy and satisfying dinner your whole family will love!

Tips for the Best Chicken Alfredo Lasagna Roll-Ups

Use Fresh Ingredients: Always opt for fresh spinach and good-quality chicken to enhance flavor. Freshness makes your Chicken Alfredo Lasagna Roll-Ups more delicious and vibrant.
Don’t Overfill: Spread the filling evenly without overfilling the noodles. Overstuffing can lead to messy roll-ups that may burst during baking.
Resting Time is Key: Let the roll-ups rest for 5-10 minutes after baking. This allows them to set, making it easier to serve and enjoy your Chicken Alfredo Lasagna Roll-Ups without them falling apart.
Mind the Noodles: If using no-boil noodles, remember to add extra sauce, about 1/2 cup, to ensure they cook properly and turn out tender.
Bake Uniformly: To achieve uniform cooking, make sure the roll-ups are snug in the baking dish but not too tight. They need a little space to expand as they bake!

How to Store and Freeze Chicken Alfredo Lasagna Roll-Ups

Room Temperature: Allow any leftovers to cool completely before storing at room temperature for up to 2 hours. After that, they should be refrigerated to ensure freshness.
Fridge: Store Chicken Alfredo Lasagna Roll-Ups in an airtight container in the fridge for up to 3 days. Reheat in the oven at 350°F (175°C) for about 15-20 minutes until heated through.
Freezer: For longer storage, freeze the roll-ups in a tightly sealed container or heavy-duty freezer bag for up to 3 months. Reheat directly from the freezer, adding extra time to ensure they warm thoroughly.
Reheating: To reheat, place frozen roll-ups in a baking dish with a little extra Alfredo sauce on top and cover with aluminum foil. Bake at 350°F (175°C) for about 30-35 minutes, removing the foil for the last 10 minutes for a bubbly finish.

Chicken Alfredo Lasagna Roll-Ups Recipe FAQs

How do I choose the best lasagna noodles for this recipe?
The best choice for Chicken Alfredo Lasagna Roll-Ups is either traditional cooked lasagna noodles or no-boil noodles. If you opt for no-boil noodles, be sure to add an extra 1/2 cup of sauce or water to your baking dish to ensure they cook adequately and remain tender.

What’s the best way to store leftovers?
Absolutely! Allow the Chicken Alfredo Lasagna Roll-Ups to cool completely before placing them in an airtight container in the refrigerator. They can be stored for up to 3 days. When ready to enjoy, reheat in the oven at 350°F (175°C) for about 15-20 minutes or until warmed through.

Can these roll-ups be frozen for a later date?
Very! To freeze, allow the roll-ups to cool completely, then place them in a tightly sealed freezer bag or an airtight container. They will last for up to 3 months. When you’re ready to eat, take them directly from the freezer, add some extra Alfredo sauce on top, and bake at 350°F (175°C) for about 30-35 minutes, removing the lid for the last 10 minutes to let them crisp up a bit.

I have dietary restrictions; can I make this dish dairy-free?
Yes, you can make Chicken Alfredo Lasagna Roll-Ups dairy-free! Simply substitute the ricotta with a dairy-free cream cheese or a blended tofu mixture as a base. Omit the egg and use a suitable binder like ground flaxseed mixed with water. Vegan cheese can be used in place of mozzarella and parmesan for a completely dairy-free meal.

What can I do if the filling is too runny?
If your filling turns out too runny, try adding more ricotta cheese or a tablespoon or two of breadcrumbs to absorb excess moisture. Alternatively, allow the filling to sit in the refrigerator for about 30 minutes before assembling to help thicken it up.

How can I ensure my Chicken Alfredo Lasagna Roll-Ups are not dry?
To prevent dry roll-ups, make sure they are generously covered with Alfredo sauce before baking, and consider adding a bit of sauce between each layer as you assemble. Additionally, cover the baking dish with foil during the initial baking phase, then uncover for the last few minutes to achieve a beautiful, bubbly top without drying out your filling.